REACH24H Consulting Group

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In December 2018, REACH24H Consulting Group China successfully completed the union authorization of EU-BPR for two Asian companies, and successfully provided 13 European companies with support for union authorization/ same biocidal products authorization. This means that the companies represented by REACH24H have successfully crossed the technical trade barriers and taken an important step towards expanding in the EU market.

The active substance involved in this product authorization is calcium hypochlorite (CAS: 7778-54-3), which covers the following uses:

  1. PT2: Disinfectants and algaecides not intended for direct application to humans or animals;
  2. PT3: Veterinary hygiene;
  3. PT4: Food and feed area;
  4. PT5: Drinking water.

On December 14, 2016, the Biocidal Products Committee (BPC) issued a resolution approving calcium hypochlorite for PT 2, 3, 4, 5. The EU Chemicals Agency (ECHA) subsequently issued a product authorization deadline for the product containing the active substance calcium hypochlorite on January 1, 2019 (see Figure 1).

FIG. 1 The deadline for EU union authorization of calcium hypochlorite products

EU BPR, which was formally implemented on September 1, 2013, not only has a long compliance cycle, heavy workload and high cost, but also strict and complex compliance requirements. Despite of the tight deadline for calcium hypochlorite, with the years of technical precipitation and project experience, REACH24H has maintained regular and efficient communications with European officials, specifically senior experts from technical teams, to give full support, and tailored solutions for customers to successfully solve the urgent corporate needs. As a happy result, in just a month REACH24H EU BPR team successfully assisted 13 European companies to complete the union/ national authorization compliance work for one biocidal product, and the team was proud to achieve this in a reduced time and at a lower cost.

The completion of BPR registration can not only well protect the interests of the claimant, but also greatly improve the market competitiveness of enterprises, allowing them to sieze the opportunity to explore the EU market, and achieve greater economic benefits. So far, EU BPR regulatory team in REACH24H has helped companies complete more than 100 EU applications, including nearly one hundred product authorization applications and over a dozen active substance supplier list applications and active substance approvals. In addition, the team has also supported a number of technical equivalence assessments. Last but not least, they have helped some small enterprises reduce their EU authority administration fee by applying for the prescribed SME discount (small and medium-sized enterprise) for evaluation applications. All in all, December was a truly challenging and rewarding month in terms of EU BPR.

About REACH24H Agrochem Department: Providing a bridge and link between European Union officials and Asian companies, REACH24H actively speak out on behalf of non-EU companies, enabling them to explore the trade of biocides in the EU and around the world. If you have further questions, please feel free to contact us!

REACH24H Agrochem Department: +86 571-87006630


Published in Corporate News

On September 13, 2017, the Ministry of Agriculture of the People's Republic of China officially the Regulation on the Management of Pesticides which included a provision which added pesticide risk assessment reports to the pesticide registration data requirements. Although Chinese pesticide companies may already understand this new regulation, few of them were able to truly grasp the Ministry’s intention behind this measure. According to REACH24H risk assessment team’s data, more than 30% of Chinese pesticide companies have experienced wasteful registration fees and registration time since the new regulations were issued. What is more, some enterprises were forced to carry out large-scale changes and adjustments due to the inability to pass the registration review in accordance with the new regulations.

Among the more than 100 risk assessment report projects already carried out by our company, more than 50% of the products failed pass the first-stage risk assessment. After the second phase of in-depth changes and a new round of assessments, companies were reportedly still unable to obtain more than 20% of the total number of risk-controlled products, involving more than a dozen companies, of which old pesticide products account for the vast majority, like indoor sprays, etc.

So what is the purpose of the newly added risk assessment of the Ministry of Agriculture? Why do you want companies to learn and carry out on their own?

The answer is: let companies to consciously eliminate old products and allow them to conduct risk pre-assessments internally.

As we all know, most countries in the world deal with the risk assessment of pesticide products by requiring that companies submit various types of data. Regulators conduct risk assessments based on this data, with the possible adverse outcome that if the assessment fails, then registration, test costs and consulting fees are all lost.

At the moment, the EU and China have proposed new requirements for companies to submit their own risk assessment reports. This is also founded on the government's desire for companies to have a more thorough understanding of their own products. This means not simply analyzing a product based on its expected market performance, but also fully understanding their value from the point of view of efficacy, health, environment, dietary impacts, and resistance. Chinese pesticide companies must accurately understand the product's life cycle and future potential, so as to develop business strategies, improve business conditions, and help with the sustainable development of the industry.

To achieve this, officers responsible for pesticide registration play a pivotal role, as their professional skills and the company’s vision will greatly determine whether it can achieve long-term stability. The registrar applicant needs to adapt his role in document editing and data collection to actually become a goalkeeper for product safety evaluation. If companies are able to adopt these guidelines, instead of blindly repeating previous experiences when applying for a registration, they may actually contribute to the long-term growth of the company and its products.

So how do you accurately apply risk assessment tools to conduct risk pre-assessment before registration?

1. Universal Application Method: before the product registration experiment

When a company and a laboratory sign a test contract and carry out efficacy, toxicology, physicochemical and environmental tests, the laboratory cannot guarantee that the product will pass the review and obtain the registration certificate. Therefore, before signing a contract with the laboratory, the company should conduct a risk pre-assessment and determine the safety status of the product in advance to ensure that the cost is used in the right place.

Although there is no guarantee that the results of the pre-assessment will be consistent with the conclusions of the final risk assessment report, most of them will not be biased as long as they are carried out by professionals.

2. Applying pre-assessment methods before production

When Chinese pesticide companies develop new products, they generally assess the possible effects and market prospect, yet often overlook the preconditions for new products to be listed. Can the product’s risk be controlled? Is it possible to successfully obtain a registration certificate?

When developing a new product, each step of production and registration is a huge investment, and one mistake can lead to tens of millions in losses, all of which has made risk assessment the basis and key for enterprise risk control. In China, specifically, the risk pre-assessment of new products is very difficult to carry out, as many products lack the corresponding data support, and all the complete registration data may require tens of millions of RMB in cost. Therefore, it is recommended that non-test methods such as Read-Across and QSAR can be used to predict the nature of new products and conduct risk pre-assessment in advance.

3. Special application method: new formula and new dosage form, new crop, new application method before application

Finally, due to the resistance of the pesticide itself and changes in the environment, the risk assessment result for the product will also change with the understanding of the human pesticide, use, and the improvement of the level of protection. Therefore, it would be highly recommended that personnel in charge of pesticide registration in Chinese companies incorporate new ideas and concepts as soon as possible, using risk assessment tools, thus saving registration costs, improving their understanding of the quality of their products, planning production and product layouts in advance more efficiently, and realizing the enterprise's own contribution to the sustainable development of the pesticides industry in China.

Published in Pesticide News

At present, many products in the market contain silver ions, such as silver ions anti-bacterial clothing, silver ions anti-bacterial mobile phone film, silver ions anti-bacterial wet wipes, etc. But a recent call from ECHA’s Biocidal Products Committee to refuse approval to three silver-containing active substances may change that.

What did the BPC determine?

The Biocidal Products Committee (BPC) concluded that the following active substances should not be approved: silver zeolite, silver copper zeolite (CAS Number: 130328-19-7), and silver sodium hydrogen zirconium phosphate (CAS Number: 130328-19-7 EC Number: 422-570-3) for product-types 2 (Disinfectants and algaecides not intended for direct application on humans or animals) and 7 (Film preservatives). The committee’s opinion is that the active substances cannot be approved for product-types 2 and 7 because their efficacy is not sufficiently demonstrated.

The committee also discussed its draft opinions on the following active substances (with no final decision as of yet): silver zeolite for product-types 4 (Food and feed area disinfectants) and 9 (Fibre, leather, rubber and polymerised materials preservatives); silver zinc zeolite (CAS Number: 130328-20-0) for product-types 2 (Disinfectants and algaecides not intended for direct application to humans or animals), 4 (Food and feed area disinfectants), 7 (Film preservatives) and 9 (Fibre, leather, rubber and polymerised materials preservatives); silver copper zeolite (CAS Number: 130328-19-7) for product-types 4 (Food and feed area disinfectants) and 9 (Fibre, leather, rubber and polymerised materials preservatives); and silver sodium hydrogen zirconium phosphate (CAS Number: 130328-19-7 EC Number: 422-570-3) for product-types 4 (Food and feed area disinfectants) and 9 (Fibre, leather, rubber and polymerised materials preservatives). The discussion on these opinions will continue in a forthcoming meeting.

Recently, the European Commission has also published a list on the non-approval of certain active substances in biocidal products related to silver ions, including silver( EC Number: 231-131-3 CAS Number: 7440-22-4) for PT9 (Fibre, leather, rubber and polymerised materials preservatives), silver chloride (EC Number: 232-033-3 CAS Number: 7783-90-6) for PT10 (construction material preservatives) and PT11 (preservatives for liquid-cooling and processing systems), silver zinc zeolite (CAS Number: 130328-20-0) for PT5 (drinking water), and silver copper zeolite (CAS Number: 130328-19-7) for PT5 (drinking water).

In the same case as the one stated before, the industries that may result affected by this non-confirmed decision about the three active substances include: manufacturers which produce disinfectants and algaecides not intended for direct application to humans or animals, drinking water disinfectants, preservatives for construction materials and liquid-cooling and processing systems (and their downstream enterprises), as well as film preservatives enterprises such as paint, plastics, sealants, walls, adhesives, adhesives, paper, art works and so on, fibre, leather, rubber and polymerised materials, preservatives manufacturers and their downstream enterprises. The enterprise concerned will have to promptly stop applying for related product types containing silver ions and opt instead for other approved products with compliance. REACH24H will keep on reporting on ECHA’s official developments and decisions.

Boasting an extensive experience the management of biocidal product regulations, REACH24H offers tailored and updated regulatory solutions to its clients. Do not hesitate to contact us if you have any doubts.

Contact Phone Number (China Mainland): +86 - 571 - 87006630


Published in EU BPR News

November 19, 2018. Last week was a relevant one for the Chemical industry, with ChemCon concluding its Europe tour in the city of Budapest, Hungary after 5 days of extensive sessions on chemical legislation covering not only the Americas, but also Asia and Europe.

REACH24H joined as partner to the event once more, welcoming longtime partners and clients, including 3M, Total, Roche and UMCO. The REACH24H team was composed by Mr. Kintan Xu, Manager of Chemical Registration, Ms. Erin Wu, Manager of the GHS Department, and Ms. Lynn Liang, Editor of Chemlinked and Mr. Robert Kiefer, General Manager of REACH24H USA Inc.

Robert Kiefer chaired a session on Chemical Control legislation in North America on Wednesday 14th, with experts joining from US EPA, Intertek and Keller and Heckman.

Understanding GHS Implementation in Asia-Pacific

Mr.Kiefer himself was asked to present on two topics, namely present on the "GHS Implementation in Asia-Pacific and Overview of Regulations on the Management of Chemical Substances and Updates and Development and Revision of the New Chemical Substance Notification (NCSN) Scheme, Order No.7".

As Mr. Kiefer introduced during his presentation on GHS, with the implementation of the “One Belt and One Road Initiative”, China aims to actively develop economic partnerships with fellow countries in the region, which thus demands that enterprises specifically address this region and their individual trade market realities and regulations to avoid unnecessary losses or business potential disruptions.

When addressing the content of GHS in China, Mr.Kiefer referred the much discussed State Institutional Reforms which eliminated and reformed several of its Ministries this past March 2018. Special mention was made of Decree No. 591, the top law for GHS management, and other several Department Measures and national standards including SAWS Order 53 and 60 addressing the registration, physical hazards identification and classification management.

Although different Asian countries have fully implemented GHS according to requirements of the UN GHS, this does not mean they are truly “harmonized”. Among other reasons, Mr.Kiefer quoted the following: Different countries may adopt different versions of the Purple Book, making localized adaptions based on specific country needs. Also, it is difficult to keep track of all newly added or modified requirements, which stands in the way of some countries fully following up on other counterparts advances. Additionally, even authorities within countries may regulate issues differently, by each addressing specific requirements for the notification, business licensing, reporting and legal inspections at Customs, among others.

Kiefer summed up this issue with one simple recommendation: catalogues of hazardous chemicals and lists of classifications officially released in each specific country of the region should be thoroughly checked in before classifying products for a specific Asia Pacific country market.

The table shows us lists of classifications in some countries:


Catalogue of Hazardous Chemicals (2015)


CLA GHS (Recommended, online search for members)

South Korea

MOE Classification List (Compulsory); MOEL Classification List (Recommended)


CHRIP database (Recommended)




Officially Classified Database (Advisory)


Adopt Japanese CHRIP


EHS/CMR Reference List


HSIS系统(the same as EU)





New Zealand

HSNO分类/CCID: Compulsorily classify HSNO of pure substance

Finally, Mr. Kiefer explained that of the contents of a SDS, Sections 1, 2, 3, and 8 are of biggest differences in different Asian countries. A relevant point was that both in China-Mainland as well as in South Korea, if some ingredients of a product are confidential, trade-names or concealed CAS number may be resorted to in order to express its hazards. In Taiwan, due to the duty to submit a declaration with OSHA, ingredients with health hazards may not be kept confidential, while in Japan common names may be used to keep this information concealed. This is different from Australia, where this option is only available for ingredients with relatively minor hazards and without occupational exposure limit.

For more on ChemCon, Chemlinked will be covering it through its specialized Asia-Pacific news portal.

Published in Corporate News

Five years have passed since the European Biocidal Products Regulation (BPR) became effective back in September 2013. The European Chemicals Agency (ECHA) decided to celebrate this date by holding a Biocides Day on October 24-25 to report on the current implementation of the BPR Regulation and its way forward.

By the end of October 2018, the EU had approved 144 biocide active substances, including 6 microorganisms, covering pesticides, preservatives, anti-allergic agents, antibacterial and antibacterial products, and utensils and furniture for kitchen-use, as well as downstream manufacturers of paint, coatings, textiles, building materials, carpets, ceramic products and electronic appliances. In addition, the EU banned 15 active substances and combinations of uses, such as triclosan (CAS No. 3380-34-5) which was banned from human sanitizers, non-human and animal contact disinfectants, film preservatives and, among the preservatives for fibers, leather, rubber and polymerised material. Silver chloride (CAS No.: 7783-90-6) is banned from veterinary disinfectants, food and feed area disinfectants, drinking water disinfectants and cutting fluid preservatives. MBIT (CAS No.: 2527-66-4) was banned from cutting fluid preservatives. Related banned substances include disinfectants, fungicides, industrial insecticides, acaricides, antifouling agents and fibers, leather, rubber, polymers, building materials and related preservatives. Products containing banned active substances will not be allowed to circulate the EU market.

As more and more active substances are approved, product authorization applications continue to increase. As of October 2018, member states had completed 7,900 authorizations, mainly in the areas of wood preservatives, rodenticides and pesticides. Union Authorization refers to the type of product authorization enables a product to be sold throughout the EU. As of 2018, ECHA has received 80 applications of Union Authorization, of which 2 have received approval.

As regards law enforcement, although BPR has only been effective for five years, the regulatory system has reached a high standard, with various law enforcement projects launched. At present, various member states of the European Union have initiated the labeling of biocide products. According to data gathered from the conference, the focus of law enforcement in 2019 will be biocide treated articles. Biocide treated articles are the latest to be incorporated into BPR regulations. Most of the enterprises affected are those engaged in the clothing, furniture, leather, sanitary ware, rubber, plastics and paints industries.

ECHA stated future steps are accelerating the review process of biocide active substances. As the compliance deadline approaches and the overall market compliance awareness increases, product licensing applications are on the rise. Each member country will improve its efficiency, release resources, and complete their authorization approval as soon as possible to prevent backlogs. To sum up, as far as the jurisdiction of BPR is concerned, companies should pay attention to the approval progress of biocide active substances and products regularly, and actively prepare compliance data, in order to finish compliance duties before the deadline and seize the European market share.

REACH24H CONCULTING GROUP CHINA regularly follows up on biocide regulations and will continue releasing the most updated information. We recommend that in order to ensure an orderly and responsible product authorization, companies with plans to expand their business into the EU market stay up to date on the latest developments.

Can our team help you?

Reach out to REACH24H Agrochemicals Division: +86 0571-87006630

Contact Email:

Published in EU BPR News

Hangzhou, China. On October 30, 2018, the first QSAR Model Training Course hosted by REACH24H was successfully completed. The headquarters of the company welcomed professionals who came all the way from BASF, Dow, Bayer, DuPont, L'Oreal, Yunfa Chemical, Fuhua Tongda, TEDA, among others, eager to learn the particulars about this model for its increasing application at a regulatory level. This event also attracted participants from universities and research institutes such as Nanjing Institute of Environmental Sciences, Guangdong Microbiological Analysis and Testing Center, Shanghai Testing Center, Zhejiang Research Institute of Chemical Industry, Nanjin  University and the Chinese Academy of Sciences to level in the discussion of QSAR and its development as an essential test method.

Dr. Benfenati’s presentation

Professor Gini addressing the QSAR Training participants

The training session was led by Dr. Emilio Benfenati, Head of the Laboratory of Environmental Chemistry and Toxicology at the Mario Negri Institute, Milan and Professor Giuseppina Gini, Associate Professor, Department of Electronics, Information, and Bioengineering, Politecnico di Milano, Italy. Benfenati and Professor Gini have both developed an extensive research background in the QSAR model and VEGA platform, and they have been working to promote non-test methods such as QSAR. This model has been widely adopted and accepted by chemical regulatory institutions, including EU ECHA and EFSA.

REACH24H has been working with many industry and academia experts to promote the application of non-test methods for the purpose of chemical management, risk assessment and toxicity prediction. Having noted the often found difficulties faced by enterprises when applying QSAR prediction results to provide data for the assessment of chemicals, REACH24H expects this non-test approach to not only reduce costs of testing, but increase the speed and potentially minimize animal testing. On this basis, by contributing to the better understanding and the widespread and effective use of accurate QSAR models, REACH24H hopes to contribute to the expansion of non-test methods not only at a national but also regional regulatory level.

Published in Corporate News

In order to ensure the protection of children against risks caused by chemical substances in toys, on October 28, 2018, an amendment to EU Directive 2017/738 on lead limits in Appendix II of the Toy Safety Directive 2009/48/EC was officially approved.

In the table under point 13 of part III of Annex II to Directive 2009/48/EC, the entry for lead has been replaced by the following:




In dry, brittle, powder-like or pliable toy material (mg/kg)

In liquid or sticky toy material (mg/kg)

In scraped-off toy material (mg/kg)

Under original Directive




Under amended Directive EU 2017/738




In addition to this latest amendment, Directive 2009/48/EC on the safety of toys had already issued a limitation in the values of phenol allowed in toy materials back in May 2017. According to this amendment, values of phenol in toys intended for children under 36 months and in other toys intended to be placed in the mouth should be limited, following the data below:

  • When analyzed in polymeric materials, phenol should be limited in toys to 5 mg/l (migration limit);
  • When analyzed as a preservative, phenol should be limited in toys to a maximum concentration of 10 mg/kg (content limit);
  • According to the CMR substances content limit, phenol should be limited to 10000mg/kg.
EU Member States were given until this upcoming November 4th to adapt national regulations in order to meet the provisions of this Directive.

Understanding Lead and Phenol

Lead is a well-known toxic heavy metal that causes harm to several organ systems in the body. In children during the perinatal period it can affect the nervous system development and IQ, digestive system, the male reproductive system, besides its toxic effects on bones. In children, as the brain is in the stage of development, inhalation of lead in any environment is over 30 times higher than that of adults, with very serious effects on the child’s nervous system development.

Phenol is often used as a monomer for phenolic resins in the manufacture of resin-bonded wood for toys. Children are more susceptible to the exposure of chemicals than adults, and infants are particularly sensitive to phenol. Phenol was found in game consoles, tents or tunnels for children and in packaging film, being tested in bath toys and other inflatable toys, and as a preservative found in water-based liquid toys (Source: EUR LEX).

What now?

The new amended Directive will affect the toy sellers’ exports to the EU market. REACH24H would thus like to remind toy exporters:

  • Keep track of the latest developments in regulations and keep up to date with the latest regulations;
  • Keep high standards in internal quality control duties, apply thorough control of the source of raw materials and increase the quality inspection of finished products.

For any questions on this or any related topic, feel free to contact Mr. Chen at 0571-8700 7583 (international calls add +86) or directly at

Published in EU REACH NEWS

In the past month of February, ChemCon 2018 The Americas was successfully held in New Orleans. This was the second time that REACH24H attended the conference as a partner, where it played two important roles, both as host and speaker, with positive feedback from attendees.

To once again support this global initiative, REACH24H will join ChemCon 2018 in Europe, an event set to take place on November 12-16th in Budapest, Hungary as partner. REACH24H hopes to continue building relationships with experts from government and private sectors and increase awareness of organizations through its professional services.

The General Manager of REACH24H USA Inc., Mr. Robert Kiefer has been invited to Chair the session of Chemical Control Legislation in North America and present on the "GHS Implementation in Asia-Pacific and Overview of Regulations on the Management of Chemical Substances and Updates and Development and Revision of the New Chemical Substance Notification (NCSN) Scheme, Order No.7".

Prior to REACH24H, Robert served as Director of the Regulatory and Technical Affairs for the American Chemistry Council (ACC), and before that as Director of Scientific and International Affairs for the Consumer Specialty Products Association (CSPA). He has extensive regulatory and advocacy experience in domestic and global chemical control regulations, trade policy, hazard communication, consumer products and pesticides.

In addition to Robert’s presence, REACH24H will have a professional team to represent it during the event. Experts from the company, Mr. Kintan Xu, Manager of Chemical Registration, Ms. Erin Wu, Manager of the GHS Department, and Ms. Lynn Liang, Editor of Chemlinked, REACH24H’s online regulatory news platform, will be exhibiting at the REACH booth and will be available to assist and help with any company’s queries on regulatory issues during the conference.

ChemCon Europe 2018 is a global platform which brings together many experts representing companies, authorities and international organizations from over 30 countries. Presentations given by more than 50 speakers from governments and industry will focus on the field of international chemical legislation all over the world, like REACH, TSCA, GHS and country specific information on inventories, labelling requirements, etc.

Link to ChemCon Website


November 12th-16th, 2018


Corinthia Hotel Budapest

Erzsébet körút 43-49

Budapest H-1073


Contact Us

REACH24H | Brand & Marketing Dept.

Ms. Jill Wang

Tel: +86-571-8971 6533

Published in Webinar & Seminar

With the development of computer technology and the high concern for 3Rs principles aimed at enhancing animal welfare in testing, (Quantitative) Structure-Activity Relationship QSAR has become a widely used principle in the fields of chemicals, daily chemicals, pesticides, disinfectants, etc. By decreasing testing and R&D costs, as well as shortening the registration cycle, the QSAR method represents a primary source for companies to analyze data gaps. At the same time, due to the large number of domestic and foreign regulatory agencies that recognize this model, QSAR was increasingly found room for application in R&D, risk assessments, regulations and evaluation tasks.

VEGA has developed 50 models for predicting the toxicological properties of compounds including physicochemical, toxicological, ecotoxicological, and environmental behavior. The main models and tools include: VEGA QSAR, ToxRead, JANUS, PROMETHEUS, SARpy, ToxWeight, ToxDelta, CORAL, VEGA based tools, SOM Tool, which predictions can be used to meet EU REACH, EU BPR, cosmetics and food regulatory demands.

VEGA Hub excellence in the field of property evaluation of chemicals at a global level determined REACH24H’s interest in partnering up to extend its high qualified technical resources to its clients. Thus, in order to celebrate this new formed partnership, establish a communication platform for enterprises, regulators, laboratories, research institutes and other stakeholders and allow them to better understand the QSAR model, assisted by VEGA Hub, REACH24H will hold a training session to further promote the QSAR model on the VEGA platform. By supporting QSAR at R&D, regulatory, risk assessment and review levels we can promote a wider use of non-test methods at the regulatory level.

Course Overview

  • Background introduction and theoretical basis of the QSAR model
  • Practical examples of common QSAR models in toxicology and ecotoxicology
  • Introduction to the VEGA platform, including the Read-Across application - ToxRead model for PBT substance priority screening system - JANUS system
  • Case demonstration of VEGA and ToxRead models

Guest QSAR Experts

Dr. Emilio Benfenati

Head of the Laboratory of Environmental Chemistry and Toxicology at the Mario Negri Institute, Milan, Italy.

Researcher, Stanford University, USA

Dr. Emilio Benfenati specializes in toxicity and environmental modeling, molecular descriptors, QSAR, toxicity prediction, contamination and risk assessment. He is a leading R&D member of VEGA, ToxRead and other models which have been used by several European institutions such as ECHA and EFSA. He has coordinated more than 20 European projects and has participated in over 50 projects, many of which involved toxicity and environmental models.

Dr. Benfenati has authored/co-authored 350 international papers, and contributed as organizer of the SETAC 2011 conference (2350 participants) and QSAR 2014 (200 participants).

Professor Giuseppina Gini

Associate Professor, Department of Electronics, Information, and Bioengineering, Politecnico di Milano, Italy.

Professor Giuseppina Gini has worked in Stanford University and SRI International's Artificial Intelligence Laboratory and Nuclear Magnetic Resonance Laboratory. Since 1987, she has been an Associate Professor in the Department of Electronics, Information, and Bioengineering at the Polytechnic University of Milan. Professor Giuseppina Gini's research covers a wide range of topics, including computational intelligence, knowledge representation, machine learning, mathematical modeling and its applications. She developed a free software for QSAR (SARpy) and models for various endpoints, especially mutagenicity.

Professor Giuseppina Gini is also the author/co-author of more than 280 international journal articles and is the editor of two books. Since 1985, she has served as a Principal Investigator for approximately 30 international and national research projects (from NATO, EU, CNR, MURST) and served as coordinator for one of the projects.


** The Training will be conducted in English, please be reminded to bring your personal laptop to practice.

Contact Us

Ms. Jill Wang

Tel: +86-571-89716533


October 29, 2018






(30 min)

Introduction to in silico models



(1 hour)

Theoretical framework: chemical format, link with environmental and toxicological properties, chemical descriptors, the algorithms (Part 1)


Coffee Break



(1.5 hours)

(Continuation of Previous Topic)

Theoretical framework: chemical format, link with environmental and toxicological properties, chemical descriptors, the algorithms (Part2)


Lunch Break


Published in Webinar & Seminar

There are 12 RASFF notifications on food contact materials in April 2018,in which there are 9 food contact material products from China (including Hongkong), accounted for 75%. The main hazards for the notifications are migration of heavy metal and melamine from products. More information is shown below:


Notification type

Notified by



Action taken

Risk decision

countries concerned*




melamine plates

migration of melamine (3.7; 6.6 mg/kg - ppm) from melamine plates from Canada, via the Netherlands

public warning - press release


Austria (D) Belgium (D) Canada (O) France (D) Germany (D) INFOSAN Luxembourg (D) Netherlands Spain (D)


border rejection


silicone baby feeder

volatile organic compounds (1 %) in silicone baby feeder from China

official detention

Not serious

China (O) Finland


border rejection


melamine tableware

improper import declaration for melamine tableware from China

import not authorised

Not serious

China (O) Spain


border rejection


silicone pancake mould

high content of volatile organic constituents (1.6 %) in silicone pancake mould from China

official detention

Not serious

China (O) Finland


information for attention


rusty lids of glass jars containing mild peppers in brine

rusty lids of glass jars containing mild peppers in brine from the former Yugoslav Republic of Macedonia

recall from consumers


Croatia (D) former Yugoslav Republic of Macedonia (O)


border rejection


spoons and forks

migration of chromium (spoon: 15.2; fork: 7.6 mg/kg - ppm) and of manganese (spoon: 0.3 mg/kg - ppm) and too high level of overall migration (spoon: 95; fork: 32 mg/kg - ppm) from spoons and forks from Hong Kong

placed under customs seals


Hong Kong (O) Italy


border rejection


barbecue silicone brush

volatile organic compounds (1.5 %) in barbecue silicone brush from China

official detention

Not serious

China (O) Finland Hong Kong


border rejection


barbecue stainless steel spits

migration of nickel (0.3 mg/kg - ppm) from barbecue stainless steel spits from China

placed under customs seals


China (O) Italy




drinking glass

migration of cadmium (0.67 mg/item) and of lead (7.41 mg/item) from drinking glass from Italy

withdrawal from the market


Austria (D) Commission Services Croatia (D) Germany (D) Italy (O) Slovakia (D) Slovenia (D) Spain (D)




melamine cutting board

migration of formaldehyde (234 mg/kg - ppm) from melamine cutting board from China

withdrawal from the market


Austria (D) China (O) Germany (D) INFOSAN Spain (D)


border rejection


enamelled iron cups

inner coating oxidized of enamelled iron cups from China

placed under customs seals


China (O) Italy




kitchen tongs made of nylon

migration of primary aromatic amines (0.03 mg/kg - ppm) from kitchen tongs made of nylon from China, via the Netherlands and via Germany

withdrawal from the market


China (O) Germany INFOSAN Netherlands Poland (D)

* D = distribution O = origin

REACH24H has rich experience in dealing with GB 9685-2016 Standard for uses of additives in food contact materials and their products,United States food contact materials (FDA,FCN, 21 CFR) and EU food contact materials (EU 10/2011/BfR) and can make custom-made compliance service for enterprises.

If you have further questions, please consult +86 571-8700 7548 or send e-mail to

Published in Food Contact Material
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